Author: Maddalena Dilucca; Athanasia Pavlopoulou; Sergio Forcelloni; ANDREA GIANSANTI; Alexandros G Georgakilas
Title: Codon usage and evolutionary rates of the 2019-nCoV genes Document date: 2020_3_27
ID: l9vtsj3e_14
Snippet: Codon adaptation index CAI [? ] is used to quantify the codon usage similarities between the virus and host coding sequences. The principle behind CAI is that codon usage in highly expressed genes can reveal the optimal (i.e., most efficient for translation) codons for each amino acid. Hence, CAI is calculated based on a reference set of highly expressed genes to assess, for each codon i, the relative synonymous codon usages (RSCU i ) and the rel.....
Document: Codon adaptation index CAI [? ] is used to quantify the codon usage similarities between the virus and host coding sequences. The principle behind CAI is that codon usage in highly expressed genes can reveal the optimal (i.e., most efficient for translation) codons for each amino acid. Hence, CAI is calculated based on a reference set of highly expressed genes to assess, for each codon i, the relative synonymous codon usages (RSCU i ) and the relative codon adaptiveness (w i ):
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