Author: LI, Xunliang; LI, Pengchong; CAO, Liyan; BAI, Yunyun; CHEN, Huijie; LIU, He; REN, Xiaofeng; LI, Guangxing
Title: Porcine IL-12 plasmid as an adjuvant improves the cellular and humoral immune responses of DNA vaccine targeting transmissible gastroenteritis virus spike gene in a mouse model Document date: 2019_9_2
ID: rme6b022_3
Snippet: TGEV is a coronavirus and contains a positive-sense single-stranded RNA genome [28] , which encodes four structural proteins and three non-structural proteins. Spike (S) protein is the major component of the virion surface and possesses four antigen sites, doi: 10.1292/jvms. which may induce production of neutralizing antibodies. We chose the TGEV S1 gene in the present study, as it includes these antigen sites [20, 24] ......
Document: TGEV is a coronavirus and contains a positive-sense single-stranded RNA genome [28] , which encodes four structural proteins and three non-structural proteins. Spike (S) protein is the major component of the virion surface and possesses four antigen sites, doi: 10.1292/jvms. which may induce production of neutralizing antibodies. We chose the TGEV S1 gene in the present study, as it includes these antigen sites [20, 24] .
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