Selected article for: "dna vaccine and immunological adjuvant"
Author: LI, Xunliang; LI, Pengchong; CAO, Liyan; BAI, Yunyun; CHEN, Huijie; LIU, He; REN, Xiaofeng; LI, Guangxing
Title: Porcine IL-12 plasmid as an adjuvant improves the cellular and humoral immune responses of DNA vaccine targeting transmissible gastroenteritis virus spike gene in a mouse model
  • Document date: 2019_9_2
    • ID: rme6b022_43
    Snippet: In summary, we report that pIL-12 could act as an immunological adjuvant in the DNA vaccine for TGEV-S1. DNA vaccine developed using TGEV-S1 and pIL-12 could induce excellent activation of both the humoral and cellular immune responses. This study may provide a useful strategy to develop DNA vaccines for the prevention of TGEV in swine. The next step will be to assess its activity in a porcine model......
    Document: In summary, we report that pIL-12 could act as an immunological adjuvant in the DNA vaccine for TGEV-S1. DNA vaccine developed using TGEV-S1 and pIL-12 could induce excellent activation of both the humoral and cellular immune responses. This study may provide a useful strategy to develop DNA vaccines for the prevention of TGEV in swine. The next step will be to assess its activity in a porcine model.

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