Selected article for: "antibody production and IgG response"
Author: LI, Xunliang; LI, Pengchong; CAO, Liyan; BAI, Yunyun; CHEN, Huijie; LIU, He; REN, Xiaofeng; LI, Guangxing
Title: Porcine IL-12 plasmid as an adjuvant improves the cellular and humoral immune responses of DNA vaccine targeting transmissible gastroenteritis virus spike gene in a mouse model
  • Document date: 2019_9_2
    • ID: rme6b022_32
    Snippet: The levels of TGEV-specific antibodies in the serum of immunized mice were examined using an indirect ELISA (Fig. 3A) . In general, starting from 21 dpi, the pVAX1-(TGEV-S1), pVAX1-(TGEV-S1) plus pVAX1-(pIL-12), and vaccine-treated groups had a higher proportion of antibodies than the control groups (P<0.01). Antibody production reached its peak at 35 dpi. The pVAX1-(TGEV-S1) plus pVAX1-(pIL-12) group induced higher IgG response than other groups.....
    Document: The levels of TGEV-specific antibodies in the serum of immunized mice were examined using an indirect ELISA (Fig. 3A) . In general, starting from 21 dpi, the pVAX1-(TGEV-S1), pVAX1-(TGEV-S1) plus pVAX1-(pIL-12), and vaccine-treated groups had a higher proportion of antibodies than the control groups (P<0.01). Antibody production reached its peak at 35 dpi. The pVAX1-(TGEV-S1) plus pVAX1-(pIL-12) group induced higher IgG response than other groups except the vaccine group.

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