Author: Lan, Jiaming; Yao, Yanfeng; Deng, Yao; Chen, Hong; Lu, Guangwen; Wang, Wen; Bao, Linlin; Deng, Wei; Wei, Qiang; Gao, George F.; Qin, Chuan; Tan, Wenjie
Title: Recombinant Receptor Binding Domain Protein Induces Partial Protective Immunity in Rhesus Macaques Against Middle East Respiratory Syndrome Coronavirus Challenge() Document date: 2015_8_18
ID: q8i2gfut_37
Snippet: The gross pathology of challenged animals was investigated and necropsies were performed at 3 dpi following euthanasia. The lungs of mock group animals were congested with palpable nodules (Fig. 3b) . Dark red discolouration and multifocal consolidation was consistent with the interstitial pneumonia indicated by X-ray examination. In contrast, haemorrhage and necrosis shown by black circle in the rRBDgroups were smaller in both high and low dose .....
Document: The gross pathology of challenged animals was investigated and necropsies were performed at 3 dpi following euthanasia. The lungs of mock group animals were congested with palpable nodules (Fig. 3b) . Dark red discolouration and multifocal consolidation was consistent with the interstitial pneumonia indicated by X-ray examination. In contrast, haemorrhage and necrosis shown by black circle in the rRBDgroups were smaller in both high and low dose immunization (Fig. 3b) .
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