Author: Vineet D. Menachery; Lisa E. Gralinski; Hugh D. Mitchell; Kenneth H. Dinnon; Sarah R. Leist; Boyd L. Yount; Eileen T. McAnarney; Rachel L. Graham; Katrina M. Waters; Ralph S. Baric
Title: Combination attenuation offers strategy for live-attenuated coronavirus vaccines Document date: 2018_4_28
ID: 3t75dbb7_3
Snippet: Importantly, the NSP16 mutation can be paired with other attenuating approaches to provide 29 robust protection from heterologous challenge and in vulnerable populations. Coupled with 30 increased safety and reduced pathogenesis, the study highlights the potential for NSP16.....
Document: Importantly, the NSP16 mutation can be paired with other attenuating approaches to provide 29 robust protection from heterologous challenge and in vulnerable populations. Coupled with 30 increased safety and reduced pathogenesis, the study highlights the potential for NSP16
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