Selected article for: "animal influenza and avian influenza"
Author: Chan, Joseph M.; Rabadan, Raul
Title: Quantifying Pathogen Surveillance Using Temporal Genomic Data
  • Document date: 2013_1_29
    • ID: u2t1x89m_4
    Snippet: At present, no human-to-human transmission of HPAI virus has been documented. However, scientists have recently discovered the set of mutations that enable the transmission of avian influenza virus between ferrets (10), the animal model most closely mimicking human pathogenesis because of shared host cellular receptors for viral attachment (11) . These developments, combined with the virus's atypically high rate of mortality and apparent resistan.....
    Document: At present, no human-to-human transmission of HPAI virus has been documented. However, scientists have recently discovered the set of mutations that enable the transmission of avian influenza virus between ferrets (10), the animal model most closely mimicking human pathogenesis because of shared host cellular receptors for viral attachment (11) . These developments, combined with the virus's atypically high rate of mortality and apparent resistance to oseltamavir (12) , have raised worldwide concerns about whether our current avian influenza virus surveillance is sufficient to identify wild strains that have the potential for mammalian adaptation.

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