Selected article for: "genomic sequence and human sequence"
Author: Baldwin, Don A.; Feldman, Michael; Alwine, James C.; Robertson, Erle S.
Title: Metagenomic Assay for Identification of Microbial Pathogens in Tumor Tissues
  • Document date: 2014_9_16
    • ID: xlqdn0c7_13
    Snippet: The genomic sequence of human cytomegalovirus (CMV) strain AD169, a laboratory-adapted strain, differs at several locations from the NCBI reference CMV sequence, a clinical strain. This includes a large deletion. DNA from a cell line infected with CMV AD169 was amplified and hybridized to PathoChip v3, which includes a set of saturation tiling probes for the CMV reference genome. While most probes produced high signals, probes located at sites th.....
    Document: The genomic sequence of human cytomegalovirus (CMV) strain AD169, a laboratory-adapted strain, differs at several locations from the NCBI reference CMV sequence, a clinical strain. This includes a large deletion. DNA from a cell line infected with CMV AD169 was amplified and hybridized to PathoChip v3, which includes a set of saturation tiling probes for the CMV reference genome. While most probes produced high signals, probes located at sites that are polymorphic or deleted in CMV AD169 had significantly reduced fluorescence signals, clearly delineating the polymorphisms or deletions in the laboratory strain (Fig. 2C ).

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