Author: Ma, J; Wan, J; Meng, J; Banerjee, S; Ramakrishnan, S; Roy, S
Title: Methamphetamine induces autophagy as a pro-survival response against apoptotic endothelial cell death through the Kappa opioid receptor Document date: 2014_3_6
ID: wu2mogfa_5
Snippet: Next, we evaluated whether 1 mM METH affected endothelial cell barrier integrity. Human brain microvascular endothelial cells (HBMECs) and HUVECs were cultured on ECIS array electrodes, and transendothelial electrical resistance was monitored continuously over the course of 72 h. As shown in Figures 1b and c, no significant decrease in average transendothelial electrical resistance measurements was observed with 1 mM METH at 24 h but at 72 h, a 5.....
Document: Next, we evaluated whether 1 mM METH affected endothelial cell barrier integrity. Human brain microvascular endothelial cells (HBMECs) and HUVECs were cultured on ECIS array electrodes, and transendothelial electrical resistance was monitored continuously over the course of 72 h. As shown in Figures 1b and c, no significant decrease in average transendothelial electrical resistance measurements was observed with 1 mM METH at 24 h but at 72 h, a 50% decrease in resistance was observed compared with control.
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