Author: Jefferies, Sarah; Braithwaite, Irene; Walker, Steven; Weatherall, Mark; Jennings, Lance; Luck, Michelle; Barrett, Kevin; Siebers, Robert; Blackmore, Timothy; Beasley, Richard; Perrin, Kyle
Title: Randomized controlled trial of the effect of regular paracetamol on influenza infection Document date: 2015_12_6
ID: vj3m50sb_6
Snippet: More detailed methodology is available in Supplementary Appendix S1. Eligible participants were aged 18-65 years and had symptoms of an influenzalike illness (a history of fever (or documented temperature of ≥37.8°C), and at least one of cough, sore throat, rhinorrhoea, headache, myalgia, fatigue or malaise) for less than 48 h. After obtaining written informed consent, a rapid immunoassay test for influenza A and/or B (Xpect Flu A&B, Remel, Le.....
Document: More detailed methodology is available in Supplementary Appendix S1. Eligible participants were aged 18-65 years and had symptoms of an influenzalike illness (a history of fever (or documented temperature of ≥37.8°C), and at least one of cough, sore throat, rhinorrhoea, headache, myalgia, fatigue or malaise) for less than 48 h. After obtaining written informed consent, a rapid immunoassay test for influenza A and/or B (Xpect Flu A&B, Remel, Lenexa, KS, USA) was used to screen participants. 23 Only those who tested positive were eligible for recruitment. Key exclusion criteria included were the need for hospital admission and the regular use of paracetamol or nonsteroidal anti-inflammatory drugs (NSAID) (excluding low dose aspirin).
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