Research Communications of the 27(th) ECVIM-CA Congress: Intercontinental, Saint Julian's, Malta, 14th to 16th September 2017

Five diabetic cats and 5 controls were included. Diabetic cats had beta-cells with clearer cytoplasm than control cats. The median area of beta-cell granules was higher in diabetic than controls [0.144 µm 2 (0.047-0.252) vs. 0.035 µm 2 (range: 0.027-0.046); P < 0.05] and their median number lower [0.5/µm 2 (0.3-2.8) vs. 5.6/µm 2 (range: 3.9-7.8); P < 0.05]; eccentricity did not differ. The median inter-cristae distance of mitochondria was higher in diabetic than controls [0.064 µm (0.052-0.075) vs. 0.034 µm (range: 0.032-0.043); P < 0.05]; their area and number did not differ. Mitochondria of diabetic cats appeared swollen. Amylin-positive material outside the granules was observed in the cytoplasm of 3 diabetic cats and in none of the controls.