Research Communications of the 27(th) ECVIM-CA Congress: Intercontinental, Saint Julian's, Malta, 14th to 16th September 2017

Disclosures: Disclosures to report. This study was funded by a Petsavers grant and by Langford Vets clinical research fund NC Finch Currently receives direct research support from Boehringer Animal health, Petsavers, Langford Vets clinical research fund, Wellcome Trust Currently receives indirect research support from Zoetis and IDEXX Previously received direct support from Agria pet insurance Previously received indirect support from MSD Animal Health Salary is currently funded by the Wellcome Trust Currently a member of the Governing Council of the Cat Fancy Veterinary Advisory Committee. Previously has received honorarium for speaking for not-for-profit organizations, and occasionally for pharmaceutical industries and for articles published in peer and non-peer reviewed publications S Tasker In the past ST has received financial support for hemoplasma research from Zoetis Animal Health and for vector-borne disease research from Bayer Animal Health. ST receives financial support for current infectious disease research from BSAVA Petsavers, Langford Trust, Petplan Chari- Unit, Langford Vets, University of Bristol, which carried out the PCRs described in the study. ST has been paid for providing continuing professional development for not-for-profit organizations, and occasionally for commercial companies, around the world. A Hibbert AH has received financial support for feline hyperthyroid disease research from BSAVA Petsavers, TOSOH Bioscience, Langford Vets and the Langford Trust AH has been paid for providing continuing professional development for notfor-profit organizations, and occasionally for commercial companies, around the world. In the majority of dogs with primary hypoadrenocorticism (PH), the disease is characterized by an absolute deficiency of glucocorticoids and mineralocorticoids. Consequently, those patients require life-long replacement of both hormones. Since application of the respective drugs do not restore physiological hormone levels and biorhythm, overdose may be possible during long-term management. Unlikely to glucocorticoid excess, overdose of mineralocorticoids may go clinically unnoticed. Due to their role as key mediators for renal damage and progression of kidney disease, mineralocorticoid overdose represents a matter of concern.