Author: Michael Jay Corley; Christopher Sugai; Michael Schotsaert; Robert E. Schwartz; Lishomwa C Ndhlovu
Title: Comparative in vitro transcriptomic analyses of COVID-19 candidate therapy hydroxychloroquine suggest limited immunomodulatory evidence of SARS-CoV-2 host response genes. Document date: 2020_4_14
ID: 30x26ip7_10
Snippet: The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.04.13.039263 doi: bioRxiv preprint transcriptional changes in PBMC cells related to in vitro SARS-CoV-2 impacted gene transcription upon infection, we examined the overlap of the 16 differentially expressed HCQ genes with recent transcriptional data from in vitro SARS-CoV-2 infection of NHBE cells and A549 cells (Supplemental Table 1 ). This.....
Document: The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.04.13.039263 doi: bioRxiv preprint transcriptional changes in PBMC cells related to in vitro SARS-CoV-2 impacted gene transcription upon infection, we examined the overlap of the 16 differentially expressed HCQ genes with recent transcriptional data from in vitro SARS-CoV-2 infection of NHBE cells and A549 cells (Supplemental Table 1 ). This comparative analysis identified only two overlapping genes (Fig.1b) , NDRG Family Member 2 (NDRG2) and
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