Author: Jefferies, Sarah; Braithwaite, Irene; Walker, Steven; Weatherall, Mark; Jennings, Lance; Luck, Michelle; Barrett, Kevin; Siebers, Robert; Blackmore, Timothy; Beasley, Richard; Perrin, Kyle
Title: Randomized controlled trial of the effect of regular paracetamol on influenza infection Document date: 2015_12_6
ID: vj3m50sb_23
Snippet: The difference between the randomized groups (placebo minus paracetamol) for the primary outcome measure of AUC for quantitative influenza PCR log10 viral load from Baseline to Day 5 was −0.24 (95% CI: −0.78 to 0.29), P = 0.36 (Table 2a) . The estimate of the difference after adjustment for paracetamol use in the past 48 h and temperature at Baseline was −0.30 (95% CI: −0.87 to 0.27), P = 0.30. Table 2a shows viral load comparisons at eac.....
Document: The difference between the randomized groups (placebo minus paracetamol) for the primary outcome measure of AUC for quantitative influenza PCR log10 viral load from Baseline to Day 5 was −0.24 (95% CI: −0.78 to 0.29), P = 0.36 (Table 2a) . The estimate of the difference after adjustment for paracetamol use in the past 48 h and temperature at Baseline was −0.30 (95% CI: −0.87 to 0.27), P = 0.30. Table 2a shows viral load comparisons at each individual time point. There were no differences in the secondary viral outcome variables (Table 2b ) or the cytokine measurements (Supplementary Tables S1 and S2) .
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