Title: Research Communications of the 27(th) ECVIM-CA Congress: Intercontinental, Saint Julian's, Malta, 14th to 16th September 2017 Document date: 2017_11_7
ID: roslkxeq_401
Snippet: Twenty two dogs with CCH were selected. There was a significant negative correlation between hepatocellular p21 expression (median 83.17%; range 15.30-99.40) and survival (460 days; range 12-1559), but no correlation between p21 expression and age (median 7.3 years; range 2.0-12.0). Inclusion or exclusion of cases with copper-associated disease gave similar results. Three of four control samples from young dogs ( < 6.5 years) displayed negligible.....
Document: Twenty two dogs with CCH were selected. There was a significant negative correlation between hepatocellular p21 expression (median 83.17%; range 15.30-99.40) and survival (460 days; range 12-1559), but no correlation between p21 expression and age (median 7.3 years; range 2.0-12.0). Inclusion or exclusion of cases with copper-associated disease gave similar results. Three of four control samples from young dogs ( < 6.5 years) displayed negligible p21 expression as expected (<10%). The fourth control sample from a 16.5-year-old dog had a high percentage of p21-positive hepatocytes (85%).
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