Research Communications of the 27(th) ECVIM-CA Congress: Intercontinental, Saint Julian's, Malta, 14th to 16th September 2017

In this follow-up study 10 dogs with congenital extrahepatic single portosystemic shunt (PSS) were included. Before and 3 months after surgical closure with cellophane banding or silk ligature a ICG clearance study was both done transcutaneously and fluorometrically by taking serial blood samples 0, 1, 3, 6, 9, 18, 42 and 64 min after iv injection of 0.2 mg/kg ICG. Transcutaneous ICG clearance was measured using two miniaturized devices to detect ICG fluorescence with an excitation wave length of 760 nm and an emission wave length of 820 nm. For both methods, half life time (HLT Se , HLT tc ), plasma disappearance rate (PDR Se , PDR tc ) and 15 min retention rate (R15 Se , R15 tc ) were calculated based on the curve within minutes 1 to 15 after ICG injection. PSS closure was defined based on Doppler sonography and angiography.