Research Communications of the 27(th) ECVIM-CA Congress: Intercontinental, Saint Julian's, Malta, 14th to 16th September 2017

Disclosures: Disclosures to report. Dres. Gabris, Kock, and Niederberger are employed by B€ uhlmann Laboratories AG where the fCALÒ turbo immunoassay is offered on a fee-for-service basis. English cocker spaniels (ECS) suffer from a distinctive form of chronic pancreatitis (CP) associated with large numbers of duct and vein-centered T-lymphocytes on histology. Recent studies show a predominance of IgG4 positive plasma cells on immunohistochemistry in affected dogs, suggesting a disease similar to human IgG4-related disease (IgG4-RD). IgG4-RD typically affects older men and multiple organs, particularly causing inflammatory mass lesions in the pancreas and dry eye, dry mouth and glomerulonephritis. We recognized a similar spectrum of diseases in ECSs presenting to our center with CP and observed an over-representation of roan dogs. The aim of this study was to describe the clinical features of these ECS.