Selected article for: "diluted sera and serum virus mixture"

Author: Lan, Jiaming; Yao, Yanfeng; Deng, Yao; Chen, Hong; Lu, Guangwen; Wang, Wen; Bao, Linlin; Deng, Wei; Wei, Qiang; Gao, George F.; Qin, Chuan; Tan, Wenjie
Title: Recombinant Receptor Binding Domain Protein Induces Partial Protective Immunity in Rhesus Macaques Against Middle East Respiratory Syndrome Coronavirus Challenge()
  • Document date: 2015_8_18
  • ID: q8i2gfut_19
    Snippet: The virus neutralisation assay was conducted on Vero Cells. Briefly, sera were diluted twofold and mixed with 50 μL of 2 × 10 3 TCID 50 /mL virus, incubated at 37°C for 1 h in quadruplicate. Thereafter, 100-μL virus-serum mixture was added to Vero cells previously seeded at 1.5 × 10 4 /well. Inoculated plates were incubated in a CO 2 incubator at 37°C for 3 days, following which the cytopathic effects (CPEs) of the virus were observed micro.....
    Document: The virus neutralisation assay was conducted on Vero Cells. Briefly, sera were diluted twofold and mixed with 50 μL of 2 × 10 3 TCID 50 /mL virus, incubated at 37°C for 1 h in quadruplicate. Thereafter, 100-μL virus-serum mixture was added to Vero cells previously seeded at 1.5 × 10 4 /well. Inoculated plates were incubated in a CO 2 incubator at 37°C for 3 days, following which the cytopathic effects (CPEs) of the virus were observed microscopically at 40 × magnification. All tests were repeated twice independently.

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