Selected article for: "AUC curve area and curve area"
Author: Jefferies, Sarah; Braithwaite, Irene; Walker, Steven; Weatherall, Mark; Jennings, Lance; Luck, Michelle; Barrett, Kevin; Siebers, Robert; Blackmore, Timothy; Beasley, Richard; Perrin, Kyle
Title: Randomized controlled trial of the effect of regular paracetamol on influenza infection
  • Document date: 2015_12_6
    • ID: vj3m50sb_13
    Snippet: The primary outcome variable was area under the curve (AUC) for quantitative PCR influenza log10 viral load from Baseline to Day 5 for those participants who were PCR influenza-positive, adjusted for Baseline temperature and paracetamol use in the 48 h prior to randomization. This was chosen as the primary outcome variable as it may be a predictor of the severity of influenza infection and a predictor of risk of hospital admission. 25 Secondary v.....
    Document: The primary outcome variable was area under the curve (AUC) for quantitative PCR influenza log10 viral load from Baseline to Day 5 for those participants who were PCR influenza-positive, adjusted for Baseline temperature and paracetamol use in the 48 h prior to randomization. This was chosen as the primary outcome variable as it may be a predictor of the severity of influenza infection and a predictor of risk of hospital admission. 25 Secondary viral outcome variables, also only applicable to participants who were PCR influenza-positive, were the proportion with a >2 log10 decrease in viral load at Day 2, the proportion with an undetectable viral load by RT-PCR on Days 2 and 5, and viral culture at Days 1 and 5.

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