Author: Rogers, J.; Schoepp, R.J.; Schröder, O.; Clements, T.L.; Holland, T.F.; Li, J.Q.; Li, J.; Lewis, L.M.; Dirmeier, R.P.; Frey, G.J.; Tan, X.; Wong, K.; Woodnutt, G.; Keller, M.; Reed, D.S.; Kimmel, B.E.; Tozer, E.C.
Title: Rapid discovery and optimization of therapeutic antibodies against emerging infectious diseases Document date: 2008_5_13
ID: xkx56h0o_46
Snippet: These three Fabs (along with six others) were converted into a chimeric IgG 1 form containing a human constant region with the mouse variable region minus the DNA binding domain fusion. All the three antibodies retained their ability to block spike protein binding to the Vero E6 cells (data not shown)......
Document: These three Fabs (along with six others) were converted into a chimeric IgG 1 form containing a human constant region with the mouse variable region minus the DNA binding domain fusion. All the three antibodies retained their ability to block spike protein binding to the Vero E6 cells (data not shown).
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