Recent Advances in Biosensor Development for Foodborne Virus Detection

Neethirajan, Suresh; Ahmed, Syed Rahin; Chand, Rohit; Buozis, John; Nagy, Éva

Nevertheless, key challenges and pending issues remain to be solved on the way to successful commercialisation and implementation of these POC device and platforms. The foremost challenge is how to demonstrate high levels of analytical precision and reproductively when large numbers of samples are handled and analysed without major interference from nonspecific materials [33] . The POC technologies need to be validated by accredited standards and guidelines. Such quality control and batch to batch variability need to be set up effectively and efficiently. Additionally, the integration and miniaturising of large devices, such as microfluidic devices, remain challenging; even though recent advances in acousto-microfluidic technology shows promise to address some of these challenges [34] . Furthermore, the emerging nanomaterials enhance sensitivity and analytical performance, but their application on cytotoxicity remains controversial and requires further address.