Title: Research Communications of the 24th ECVIM-CA Congress Document date: 2015_1_10
ID: r59usk02_191
Snippet: The feline AIP gene was identified, encoding a 330 amino acid protein with 98% homology to the human AIP protein. A BLAST search revealed this gene contained 6 exons and exon specific primers were created to enable sequencing. A single nonconservative SNP was identified in exon 1 (AIP:c.9G>T), encoding for an amino acid change from aspartic acid to glutamic acid in 2/10 acromegalic patients and 0/10 control cats. Two additional conservative SNPs .....
Document: The feline AIP gene was identified, encoding a 330 amino acid protein with 98% homology to the human AIP protein. A BLAST search revealed this gene contained 6 exons and exon specific primers were created to enable sequencing. A single nonconservative SNP was identified in exon 1 (AIP:c.9G>T), encoding for an amino acid change from aspartic acid to glutamic acid in 2/10 acromegalic patients and 0/10 control cats. Two additional conservative SNPs were also identified (AIP:c.826T>C and AIP:c.481T>C).
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