Title: RESEARCH COMMUNICATIONS OF THE 28th ECVIM-CA CONGRESS Document date: 2018_12_19
ID: r79h9yzz_472
Snippet: Allopurinol is a consensual leishmaniostatic drug that increases the risk of xanthine urolithiasis, a slight to nonâ€radioâ€opaque (NRO) urolithiasis. Fews reports described urinary obstruction or pyonephrosis due to xanthine lithiasis. One retrospective study showed lithiasis or renal mineralization with xanthinuria in 10% of leishmanian dogs treated with allopurinol. To the authors’ experience, this prevalence seems to be underestimated. Th.....
Document: Allopurinol is a consensual leishmaniostatic drug that increases the risk of xanthine urolithiasis, a slight to nonâ€radioâ€opaque (NRO) urolithiasis. Fews reports described urinary obstruction or pyonephrosis due to xanthine lithiasis. One retrospective study showed lithiasis or renal mineralization with xanthinuria in 10% of leishmanian dogs treated with allopurinol. To the authors’ experience, this prevalence seems to be underestimated. The aim of this prospective controlled study is to evaluate the NROâ€urolithiasis prevalence in Leishmania infantumâ€infected dogs (Leishâ€dogs) treated with allopurinol in an endemic area.
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