Selected article for: "cc international license and logistic regression"
Author: Michael P McRae; Glennon W Simmons; Nicolaos J Christodoulides; Zhibing Lu; Stella K Kang; David Fenyo; Timothy Alcorn; Isaac P Dapkins; Iman Sharif; Deniz Vurmaz; Sayli S Modak; Kritika Srinivasan; Shruti Warhadpande; Ravi Shrivastav; John T McDevitt
Title: Clinical Decision Support Tool and Rapid Point-of-Care Platform for Determining Disease Severity in Patients with COVID-19
  • Document date: 2020_4_22
    • ID: h4lsvgxo_47
    Snippet: Calibration curves are necessary to quantitate the concentration of molecular targets in solution which are critical inputs to the diagnostic algorithm. Figure 3 demonstrates this capability with four simultaneously generated calibration curves for cTnI, CK-MB, MYO, and NT-proBNP that cover a concentration range from 0.032 to 500 ng/mL. Error bars indicate bead-to-bead precision with four redundant beads measured per sensor class. As shown, the r.....
    Document: Calibration curves are necessary to quantitate the concentration of molecular targets in solution which are critical inputs to the diagnostic algorithm. Figure 3 demonstrates this capability with four simultaneously generated calibration curves for cTnI, CK-MB, MYO, and NT-proBNP that cover a concentration range from 0.032 to 500 ng/mL. Error bars indicate bead-to-bead precision with four redundant beads measured per sensor class. As shown, the response data for each biomarker exhibits an excellent fit to a five-parameter logistic regression. As part of the multiplexed assay development effort, specificity was confirmed for the four-plex panel, as shown . CC-BY-NC-ND 4.0 International license It is made available under a author/funder, who has granted medRxiv a license to display the preprint in perpetuity.

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