Selected article for: "mitochondrial dysfunction and oxidative stress"
Title: Research Communications of the 24th ECVIM-CA Congress
  • Document date: 2015_1_10
    • ID: r59usk02_96
    Snippet: No conflicts of interest reported. Feline hypertrophic cardiomyopathy (fHCM) is the most common heart disease in cats. HCM is considered an inherited disease of the sarcomere and fHCM has been linked to mutations in one sarcomere protein i.e. MYBPC3. However, the pathophysiologic mechanisms behind disease development and progression are largely unknown. In this study we investigate whether mitochondrial morphological changes in the myocardium acc.....
    Document: No conflicts of interest reported. Feline hypertrophic cardiomyopathy (fHCM) is the most common heart disease in cats. HCM is considered an inherited disease of the sarcomere and fHCM has been linked to mutations in one sarcomere protein i.e. MYBPC3. However, the pathophysiologic mechanisms behind disease development and progression are largely unknown. In this study we investigate whether mitochondrial morphological changes in the myocardium accompany mitochondrial dysfunction and enhanced oxidative stress formation that we recently found in fHCM.

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