Author: Tang, Hei-Man Vincent; Gao, Wei-Wei; Chan, Chi-Ping; Cheng, Yun; Chaudhary, Vidyanath; Deng, Jian-Jun; Yuen, Kit-San; Wong, Chun-Ming; Ng, Irene Oi-Lin; Kok, Kin-Hang; Zhou, Jie; Jin, Dong-Yan
Title: Requirement of CRTC1 coactivator for hepatitis B virus transcription Document date: 2014_11_10
ID: qtoygz6w_1
Snippet: Hepatitis B virus (HBV), a member in the family of Hepadnaviridae, has a DNA genome 3.2 kb in size which is partially double stranded. Over 350 million people are chronically infected with HBV worldwide, including ∼10% of the population in Hong Kong and China, 15-40% of whom will terminally develop severe liver diseases including hepatocellular carcinoma (HCC) (1) . Although multiple factors are involved in the development of HCC in HBV carrier.....
Document: Hepatitis B virus (HBV), a member in the family of Hepadnaviridae, has a DNA genome 3.2 kb in size which is partially double stranded. Over 350 million people are chronically infected with HBV worldwide, including ∼10% of the population in Hong Kong and China, 15-40% of whom will terminally develop severe liver diseases including hepatocellular carcinoma (HCC) (1) . Although multiple factors are involved in the development of HCC in HBV carriers, high level of HBV DNA has been identified as a major risk (2) .
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