Research Communications of the 27(th) ECVIM-CA Congress: Intercontinental, Saint Julian's, Malta, 14th to 16th September 2017

SDMA showed, as expected, a significant correlation with SCr, urine specific gravity (USG) and UPC ratio (P < 0.05). IRIS staging, according to SCr, resulted as follows: 26 (27.4%) dogs were included in stage 0, 39 (41%) in stage 1, 12 (12.6%) in stage 2, 17 (17.9%) in stage 3 and 1 (1.1%) in stage 4. SDMA evaluation modified IRIS staging in 12 (12.6%) dogs. SDMA was increased in 51 (53.7%) dogs; in 8 (15.7%) of these, SDMA was equal to the cut-off value (14 lg/dL). In 29 (56.9%) of the "high SDMA" cases, SCr was >1.4 mg/dL while in the others 22 (43.1%) there were already one or more alterations: decrease of USG in 14 (63.6% of 22) cases, increase of UPC ratio in 15 (68.2%) cases, ultrasound features suggestive of CKD in 9 (40.1%) cases. SDMA was the only altered parameter in 4 (4.2%) dogs. SDMA was normal and creatinine slightly increased in 1 (1.1%) dog.