Title: Research Communications of the 24th ECVIM-CA Congress Document date: 2015_1_10
ID: r59usk02_152
Snippet: No conflicts of interest reported. Calprotectin (S100A8/A9 complex) belongs to the S100/calgranulin family, and is primarily released from activated neutrophils and macrophages. Serum calprotectin concentrations (CP) were shown to be increased in dogs with inflammatory diseases such as inflammatory bowel disease, pancreatitis, systemic inflammatory response syndrome, and sepsis. Canine CP thus appears to be a biomarker of inflammation. Considerab.....
Document: No conflicts of interest reported. Calprotectin (S100A8/A9 complex) belongs to the S100/calgranulin family, and is primarily released from activated neutrophils and macrophages. Serum calprotectin concentrations (CP) were shown to be increased in dogs with inflammatory diseases such as inflammatory bowel disease, pancreatitis, systemic inflammatory response syndrome, and sepsis. Canine CP thus appears to be a biomarker of inflammation. Considerable day-today variation of fecal canine CP was found in both healthy dogs and dogs with chronic gastrointestinal disease. However, the biological variation of canine CP in serum has not been reported. The aim of this study was to determine the biological variation of serum canine CP and its minimum critical difference (MCD).
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