Title: Research Communications of the 27(th) ECVIM-CA Congress: Intercontinental, Saint Julian's, Malta, 14th to 16th September 2017 Document date: 2017_11_7
ID: roslkxeq_60
Snippet: Sixteen client-owned dogs with proven moderate-to-severe pulmonary hypertension were randomly assigned to the treatment (n = 8; ozagrel hydrochloride, 5 mg/kg bid PO) or control group (n = 8; sildenafil citrate, 1 mg/kg bid PO). All patients have already been treated with standard protocol including sildenafil (1.8 AE 0.6 mg/kg, bid). Pulmonary hypertension associated with left-side heart failure (LA/Ao >1.6 and LVIDDn >1.7) was excluded in the p.....
Document: Sixteen client-owned dogs with proven moderate-to-severe pulmonary hypertension were randomly assigned to the treatment (n = 8; ozagrel hydrochloride, 5 mg/kg bid PO) or control group (n = 8; sildenafil citrate, 1 mg/kg bid PO). All patients have already been treated with standard protocol including sildenafil (1.8 AE 0.6 mg/kg, bid). Pulmonary hypertension associated with left-side heart failure (LA/Ao >1.6 and LVIDDn >1.7) was excluded in the population. Several clinical indices, which relate to hypoxia (lactate, SpO 2 , base excess), thrombosis (d-dimer), azotemia (BUN, creatinine), congestion (NT-proBNP) and echocardiographic indices (peak velocity of tricuspid regurgitation, Ao/ MPA), were tracked down for four weeks.
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