Research Communications of the 27(th) ECVIM-CA Congress: Intercontinental, Saint Julian's, Malta, 14th to 16th September 2017

In group A platelet count (P = 0.002) and serum concentrations of alkaline phosphatase (P = 0.010) were significantly higher than group B at T0. In group B serum concentrations of total protein (P = 0.025), globulins (P = 0.002), C-reactive protein (P = 0.003), and lactate dehydrogenase (P = 0.028), and urinary parameters as pigmenturia (P = 0.0003) and bilirubinuria (P = 0.041) were significantly higher than group A at T0 (Mann-Whitney test). CHAOS severity score was more predictive of outcome than Tokyo severity score at 30 and 120 days (Odd Ratio, OR, respectively 15.1 and 10.7). In addition, a few clinico-pathological signs were statistically related with a worse prognosis (OR): urea concentration (>55 mg/ dL) at TD, hyperbilirubinemia (>1.5 mg/dL) and number of nucleated RBCs (≥30/100 WBC) at T30 and T120, thrombocytopenia (<150 9 10 9 /L) at TD, T30 and T120. Group B dogs had higher mortality rate (47%) than group A dogs (13%) after 2 weeks from T0 (P > 0.05, Kaplan-Meier curve).