RESEARCH COMMUNICATIONS OF THE 28th ECVIM-CA CONGRESS

The study included 64 dogs: 31/64 were Leptospiral‐iAKI and 33/64 Other‐iAKI (non‐infectious inflammatory disease n=10; toxic n=8; sepsis n=6; neoplasia n=3; trauma n=3; diabetic ketoacidosis n=3). Renal function was more severely compromised in Leptospiral‐iAKI compared with Other‐iAKI dogs (serum creatinine mg/dL: 6.9, 1.1‐ 8.7 vs 4.3, 1.4‐21.4, P=0.04, R.I. 0.65‐1.40). Urine proteins and electrolytes loss was detected in both groups; however, no significant differences between Leptospiral‐iAKI and Other‐iAKI were identified for urine protein to creatinine ratio (UP/C: 1.7, 0.13‐184 vs 2.2, 0.09‐72, P=0.58; R.I. 0‐0.5) and FE (%) of electrolytes (potassium: 92.3, 0.6‐480 vs 61.5, 5.3‐301, P=0.11, R.I. 3.7‐20.4; magnesium: 8.9, 2.8‐141 vs 10.6, 0.9‐81, P=0.9, R.I. 0.5‐3.9; phosphate: 31.9, 0.8‐125 vs 32.5, 0.8‐91, P=0.6, R.I. 5.7‐24.6; sodium: 2.6, 0.08‐64.3 vs 2.1, 0.04‐69.3, P= 0.7, R.I. 0.05‐0.92; calcium: 3.8, 0.12‐70 vs 4.2, 0.14‐56 vs, P=0.8, R.I. 0.05‐0.33). Similarly, no significant differences were detected for uNGAL concentration (uNGAL pg/mL: 146960, 1204‐308740 vs 22200, 637‐1241800, P=0.18, R.I. 0‐1200) and uNGAL to creatinine ratio (uNGAL/C x103 159, 1.4‐545 vs 40, 0.5‐2057, P=0.33, R.I. 0‐0.4).