Title: Research Communications of the 27(th) ECVIM-CA Congress: Intercontinental, Saint Julian's, Malta, 14th to 16th September 2017 Document date: 2017_11_7
ID: roslkxeq_75
Snippet: EMBs were obtained with owner consent from 48 dogs: 42 with advanced cardiac disease and six asymptomatic boxers (>5 years) with mild to moderate ventricular arrhythmia (VA) burden. Investigators were blinded to breed and clinical signs of the dogs. ARVC was diagnosed from EMBs by histopathology (MT) in 5 dogs. Of these, 3 had clinical signs consistent with ARVC (2 boxers, 1 English bulldog). Two were asymptomatic boxers with a moderate VA burden.....
Document: EMBs were obtained with owner consent from 48 dogs: 42 with advanced cardiac disease and six asymptomatic boxers (>5 years) with mild to moderate ventricular arrhythmia (VA) burden. Investigators were blinded to breed and clinical signs of the dogs. ARVC was diagnosed from EMBs by histopathology (MT) in 5 dogs. Of these, 3 had clinical signs consistent with ARVC (2 boxers, 1 English bulldog). Two were asymptomatic boxers with a moderate VA burden. Confocal microscopy was performed (EMO) to detect immunoreactive signal for plakoglobin in EMBs. Samples were prepared with antibodies recognizing cadherin (intercalated disc marker) and plakoglobin.
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