Title: RESEARCH COMMUNICATIONS OF THE 28th ECVIM-CA CONGRESS Document date: 2018_12_19
ID: r79h9yzz_435
Snippet: When tested against the control group, the IK group exhibited 1743 upregulated and 1196 downregulated genes, and the NIK group displayed 209 upregulated and 291 downregulated genes. Compared to the NIK group, there were 849 upregulated genes and 451 downregulated genes in the IK group. Genes associated with the gene ontology categories of collagen binding (e.g., transforming growth factor b1 and matrix metalloproteinase [MMP] 13), metalloendopept.....
Document: When tested against the control group, the IK group exhibited 1743 upregulated and 1196 downregulated genes, and the NIK group displayed 209 upregulated and 291 downregulated genes. Compared to the NIK group, there were 849 upregulated genes and 451 downregulated genes in the IK group. Genes associated with the gene ontology categories of collagen binding (e.g., transforming growth factor b1 and matrix metalloproteinase [MMP] 13), metalloendopeptidase activity (e.g., MMPâ€7, â€9, â€11, â€13, â€16, â€23B and â€28), chemokine activity, Tâ€cell migration, and positive regulation of macrophages chemotaxis were overrepresented in the IK group vs. control. Genes associated with the extracellular matrix (e.g. tissue inhibitor of metalloproteinase 1 and connective tissue growth factor) were upregulated in both IK and NIK tissues.
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