RESEARCH COMMUNICATIONS OF THE 28th ECVIM-CA CONGRESS

Thirty‐five dogs with Babesia rossi‐infections and 10 healthy control dogs were enrolled in this prospective observational study. Blood and urine were collected in both groups at presentation (T0), in 10 Babesia‐infected dogs after 24 hours (T24h), and in 7 dogs after 1 month (T1m). Routine renal biomarkers included serum creatinine (sCr) and urinary protein:creatinine (UPC). Novel kidney injury biomarkers, as determined by validated immunoassays, included urinary immunoglobulin G (uIgG), C‐reactive protein (uCRP), retinol‐binding protein (uRBP), urinary and plasma neutrophil gelatinase‐associated lipocalin (u/pNGAL). Urinary biomarkers were normalized to urinary creatinine. Serum symmetric dimethylarginine (SDMA, IDEXX SDMATM Test) was measured as a novel functional renal biomarker. Mann‐Whitney tests compared biomarkers between dogs with and without babesiosis. Wilcoxon signed‐rank tests compared biomarkers between T0, T24h, and T1m in infected dogs. P‐values <0.05 were considered significant.