Research Communications of the 27(th) ECVIM-CA Congress: Intercontinental, Saint Julian's, Malta, 14th to 16th September 2017

It is hypothesized that silica uroliths may be related to silica intake by plants or plant by-products with diet or by consumption of soil (>90% silica) secondary of diet-associated pica. 5 In this case the dog was fed a commercial gastro intestinal low fat dry diet for 1 year. Additionally, the dog regularly consumed feces of feral rabbits on its daily walks since more than 2 years. The analysis of a sample of such feces showed that it contained high amounts of insoluble ash (7% of fresh matter or 12.3% vs. 4% dry matter in pet rabbits). The intake of such feces together with soil sticking to it might have caused silica uroliths in this case, since no signs of dysuria or abnormal ultrasonographic examinations of the bladder or urinalysis did recur after the dog was kept from consuming rabbit feces for more than three month. The restriction of phosphate (P) intake is crucial in patients with chronic renal insufficiency (CRI), especially in case of hyperphosphatemia. Major sources of P are proteins, bones and cartilages as well as inorganic supplements for nutritional and technical purposes. To date, the total amount of P in a diet is used to assess the daily load of P for the patient. Besides, P excess is suspected to play a role also in the pathogenesis of CRI. The aim of this study was to test the effects of different P sources on the body based on a different availability of the mineral. In 8 adult Beagles the aD of P and Calcium (Ca) was determined after feeding a control diet (0.5% P/DM) for 18d (13d adaptation, 5d balance). This was repeated aiming at 2.2% P/DM by adding different phosphates (CaHPO 4 , NaH 2 PO 4 , poultry meal, Na 5 P 3 O 10 , Ca (H 2 PO 4 ) 2 , bone meal, KH 2 PO 4 , K 4 P 2 O 7 ) while adjusting the Ca/P ratio to~1.3/1 using CaCO 3 (exceptions diet poultry meal: Ca/P 1.7/1; diet Na 5 P 3 O 10 : 1.5% P/DM due to low acceptance) with wash-out periods of ≥10d. Serum P, Ca and PTH was determined at d18 pre-and 2 h postprandially. Pre-and postprandial urine was analyzed for creatinine and P. Statistics: ANOVA (Bonferroni) or Kruskal Wallis (Tukey) according to data distribution.