Selected article for: "high expression and protein expression"
Author: Rappuoli, Rino; Bottomley, Matthew J.; D’Oro, Ugo; Finco, Oretta; De Gregorio, Ennio
Title: Reverse vaccinology 2.0: Human immunology instructs vaccine antigen design
  • Document date: 2016_4_4
    • ID: uyoerxvu_7
    Snippet: 1796: Jenner starts growing cowpox in cows (Willis, 1997; Baxby, 1999) , marking the beginning of vaccinology. 1995 . 1995: Venter publishes the first sequencing of the entire genome from a bacterium (Fleischmann et al., 1995 (Fleischmann et al., ). 2000 Reverse vaccinology Genomics, high-throughput protein expression, and animal models: Vaccine antigens are discovered using the genomic information without the need for growing microorganisms. Ant.....
    Document: 1796: Jenner starts growing cowpox in cows (Willis, 1997; Baxby, 1999) , marking the beginning of vaccinology. 1995 . 1995: Venter publishes the first sequencing of the entire genome from a bacterium (Fleischmann et al., 1995 (Fleischmann et al., ). 2000 Reverse vaccinology Genomics, high-throughput protein expression, and animal models: Vaccine antigens are discovered using the genomic information without the need for growing microorganisms. Antigens selected in silico are expressed and screened in animal models.

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