Research Communications of the 27(th) ECVIM-CA Congress: Intercontinental, Saint Julian's, Malta, 14th to 16th September 2017

Disclosures: Disclosures to report. Author and coauthors are employees of Idexx Laboratories, Inc. ESS being treated in first opinion and referral practice with a histological diagnosis of idiopathic chronic hepatitis were enrolled prospectively between 2009 and 2017. Attending veterinary surgeons were asked to give prednisolone 1-2 mg/kg/day and submit regular blood results and progress reports to the authors. Ten female and four male ESS were enrolled with a median age at diagnosis of 5 years 7 months [range: 11 months-10 years]. No cases had been treated with corticosteroids within 6 months of the study. The mean prednisolone starting dose was 1.1 mg/kg/day [range: 1-2 mg/kg/day]. All cases received additional therapies including combinations of S-adenosylmethionine, Silybin, Ursodeoxycholic acid, and hepatic diet. The prednisolone dose was tapered appropriately over several months according to the patient's clinical and biochemical response, focusing on alkaline phosphatase (ALKP), alanine aminotransferase (ALT) and bilirubin.