Title: Research Communications of the 27(th) ECVIM-CA Congress: Intercontinental, Saint Julian's, Malta, 14th to 16th September 2017 Document date: 2017_11_7
ID: roslkxeq_568
Snippet: Neurological signs have been described to occur in 7.5% of hypothyroid dogs. However, in the present study, 29% of hypothyroid dogs had NS, and among them, 76.5% presented seizures. Probably, our diagnostic protocol used for convulsive patients, were thyroid hormones testing is always included before anticonvulsive treatment is administered, is related with this finding. Different mechanisms have been proposed to explain the development of NS in .....
Document: Neurological signs have been described to occur in 7.5% of hypothyroid dogs. However, in the present study, 29% of hypothyroid dogs had NS, and among them, 76.5% presented seizures. Probably, our diagnostic protocol used for convulsive patients, were thyroid hormones testing is always included before anticonvulsive treatment is administered, is related with this finding. Different mechanisms have been proposed to explain the development of NS in hypothyroid dogs, including alterations in axonal transport and ischemia. Hypercholesterolemia and atherosclerosis and consequent hypoxia of Central Nervous System has been observed and proposed as a cause of NS; however, in the present study hypercholesterolemia is definitely not related to seizures. Clinical evidence of myxedema though seems to be related with seizures.
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