Title: Retention of p63 in an ER-Golgi intermediate compartment depends on the presence of all three of its domains and on its ability to form oligomers Document date: 1994_7_1
ID: ra20actc_2
Snippet: T HE Secretory pathway of eukaryotic cells is composed of a series of different compartments through which newly synthesized proteins are transported en route to their final destination in the cell (Paiade, 1975) . Each of the subcellular organelles along this pathway contains a characteristic set of proteins that maintain their structural and functionai integrity. A challenging question in contemporary cell biology is to understand how resident .....
Document: T HE Secretory pathway of eukaryotic cells is composed of a series of different compartments through which newly synthesized proteins are transported en route to their final destination in the cell (Paiade, 1975) . Each of the subcellular organelles along this pathway contains a characteristic set of proteins that maintain their structural and functionai integrity. A challenging question in contemporary cell biology is to understand how resident components, unlike itinerant proteins, achieve specific localization in a given intracellular compartment.
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