Selected article for: "Clusterin expression and control population"
Title: RESEARCH COMMUNICATIONS OF THE 28th ECVIM-CA CONGRESS
  • Document date: 2018_12_19
    • ID: r79h9yzz_537
    Snippet: Clusterin (apoliprotein J) is a heterodimeric glycoprotein, widely expressed throughout the body, with an important role in tumourigenesis, apoptosis, and immunoregulation. In humans, clusterin expression has been associated with anaplastic large cell and Hodgkin's lymphoma. The objective of this study was to determine if clusterin expression differed significantly between dogs with high grade multicentric lymphoma (MLSA), and a healthy control p.....
    Document: Clusterin (apoliprotein J) is a heterodimeric glycoprotein, widely expressed throughout the body, with an important role in tumourigenesis, apoptosis, and immunoregulation. In humans, clusterin expression has been associated with anaplastic large cell and Hodgkin's lymphoma. The objective of this study was to determine if clusterin expression differed significantly between dogs with high grade multicentric lymphoma (MLSA), and a healthy control population and had potential as a biomarker. We hypothesised that serum clusterin expression would be higher in untreated dogs with lymphoma in comparison to controls, and that clusterin would subsequently decrease with clinical remission, following successful treatment.

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