Author: Kianmehr, Nahid; Bidari, Ali; Mofidi, Mani; Bahar, Nasim
Title: Silent osteonecrosis of the femoral head following high-dose corticosteroids in patients with systemic rheumatic diseases Document date: 2015_9_8
ID: qwpma8oj_20
Snippet: In another study on 540 SLE patients, mean daily dose and intravenous pulse in addition to cumulative dose of prednisolone were related to ON (12) . Zhang et al showed that the number of ON lesions was directly associated with the dosage of CS, pulse and cumulative regimen (13) . In other survey on 106 SLE patients during follow up period of 13.6 years, total duration of CS and duration of treatment was not related to ON (14) . Griffith et al sho.....
Document: In another study on 540 SLE patients, mean daily dose and intravenous pulse in addition to cumulative dose of prednisolone were related to ON (12) . Zhang et al showed that the number of ON lesions was directly associated with the dosage of CS, pulse and cumulative regimen (13) . In other survey on 106 SLE patients during follow up period of 13.6 years, total duration of CS and duration of treatment was not related to ON (14) . Griffith et al showed that cumulative CS dose is an important risk factor for osteonecrosis. In his study, prevalence of ON was 0.6% for patients taking less than 3 g and 13% for ones who receiving more (15) .
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