Author: Bhuiyan, Mejbah Uddin; Snelling, Thomas L; West, Rachel; Lang, Jurissa; Rahman, Tasmina; Borland, Meredith L; Thornton, Ruth; Kirkham, Lea-Ann; Sikazwe, Chisha; Martin, Andrew C; Richmond, Peter C; Smith, David W; Jaffe, Adam; Blyth, Christopher C
Title: Role of viral and bacterial pathogens in causing pneumonia among Western Australian children: a case–control study protocol Document date: 2018_3_16
ID: w3rxdaii_8
Snippet: • This is the first case-control study in Australia to determine the aetiology and relative contribution of respiratory viruses and bacteria to childhood pneumonia during the post pneumococcal vaccination era • The study design will estimate how much each of the respiratory pathogen attributes to childhood pneumonia at population level after adjusting for demographic factors, pre-existing chronic medical conditions and the presence of other r.....
Document: • This is the first case-control study in Australia to determine the aetiology and relative contribution of respiratory viruses and bacteria to childhood pneumonia during the post pneumococcal vaccination era • The study design will estimate how much each of the respiratory pathogen attributes to childhood pneumonia at population level after adjusting for demographic factors, pre-existing chronic medical conditions and the presence of other respiratory pathogens • Prospective recruitment of frequency matched cases and controls in each age group will adjust the effect of age of participant and pathogen seasonality in causing pneumonia in children • Cases are defined as children with radiologically-confirmed pneumonia which reduces the inter-observer variability to define pneumonia on the basis of respiratory symptoms at presentation in hospital and this standard definition of pneumonia will increase the generalizability of the study data Limitations:
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