Author: Zheng, Li-Zhen; Wang, Jia-Li; Kong, Ling; Huang, Le; Tian, Li; Pang, Qian-Qian; Wang, Xin-Luan; Qin, Ling
Title: Steroid-associated osteonecrosis animal model in rats Document date: 2018_2_6
ID: tad9jmfp_31
Snippet: Vessel architecture in the proximal tibia and distal tibia in the normal and SAON group was analysed by Microfil perfusion and micro-CT. Histogram showed that in the proximal tibia, the medium (100e200 mm) and large-sized (>200 mm) blood vessels in the SAON group were significantly less than those in the normal group; in the distal tibia, the small-sized leakage particles (<100 mm) in the SAON group were significantly more than those in the norma.....
Document: Vessel architecture in the proximal tibia and distal tibia in the normal and SAON group was analysed by Microfil perfusion and micro-CT. Histogram showed that in the proximal tibia, the medium (100e200 mm) and large-sized (>200 mm) blood vessels in the SAON group were significantly less than those in the normal group; in the distal tibia, the small-sized leakage particles (<100 mm) in the SAON group were significantly more than those in the normal group (p < 0.05, n Z 4). Histologic sections showed that the small-sized leakage particles were in the bone marrow outside the blood vessels (Fig. 6C1) . VEGF expression was higher in the SAON group in both proximal and distal tibia (Fig. 6 ).
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