Author: Michael Jay Corley; Christopher Sugai; Michael Schotsaert; Robert E. Schwartz; Lishomwa C Ndhlovu
Title: Comparative in vitro transcriptomic analyses of COVID-19 candidate therapy hydroxychloroquine suggest limited immunomodulatory evidence of SARS-CoV-2 host response genes. Document date: 2020_4_14
ID: 30x26ip7_43
Snippet: RNA-Seq count data was read into R using Bioconductor and rowSums >1 were filtered to remove lowly expressed genes. Differential expression was conducted with edgeR and adjusted for P value using the FDR method option. Heatmaps and unsupervised clustering utilized the pheatmap R package. Rows were scaled by calculating the Z score of expression values for each sample. Clustering utilized the complete method......
Document: RNA-Seq count data was read into R using Bioconductor and rowSums >1 were filtered to remove lowly expressed genes. Differential expression was conducted with edgeR and adjusted for P value using the FDR method option. Heatmaps and unsupervised clustering utilized the pheatmap R package. Rows were scaled by calculating the Z score of expression values for each sample. Clustering utilized the complete method.
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