Author: Nicholls, John M
Title: The Battle Between Influenza and the Innate Immune Response in the Human Respiratory Tract Document date: 2013_3_29
ID: vyci1ho3_35
Snippet: Thus TLR7 appears to play a dual role -the recognition of vRNA in early infection and then in terms of immunization TLR7 is activated in the MHC class II endocytic pathway. As a backup to the late endosomal compartment there are 2 other pathways that recognize vRNA in the cytosolic component -RIG-I and NLR......
Document: Thus TLR7 appears to play a dual role -the recognition of vRNA in early infection and then in terms of immunization TLR7 is activated in the MHC class II endocytic pathway. As a backup to the late endosomal compartment there are 2 other pathways that recognize vRNA in the cytosolic component -RIG-I and NLR.
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