Author: Xiaoqiang Huang; Robin Pearce; Yang Zhang
Title: Computational Design of Peptides to Block Binding of the SARS-CoV-2 Spike Protein to Human ACE2 Document date: 2020_3_31
ID: imkeghfd_16
Snippet: In previous studies, we also proposed incorporating protein-protein interface evolutionary profiles to model PPIs 19, 29, 30 . However, no interface structural analogs were identified from the non-redundant interface library (NIL) 30 , and no interface sequence analogs were found from the STRING 31 database with a PPI link score ≥0.8. Therefore, the interface evolutionary profile scoring was excluded from design......
Document: In previous studies, we also proposed incorporating protein-protein interface evolutionary profiles to model PPIs 19, 29, 30 . However, no interface structural analogs were identified from the non-redundant interface library (NIL) 30 , and no interface sequence analogs were found from the STRING 31 database with a PPI link score ≥0.8. Therefore, the interface evolutionary profile scoring was excluded from design.
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