Author: van Griensven, Johan; De Weiggheleire, Anja; Delamou, Alexandre; Smith, Peter G.; Edwards, Tansy; Vandekerckhove, Philippe; Bah, Elhadj Ibrahima; Colebunders, Robert; Herve, Isola; Lazaygues, Catherine; Haba, Nyankoye; Lynen, Lutgarde
Title: The Use of Ebola Convalescent Plasma to Treat Ebola Virus Disease in Resource-Constrained Settings: A Perspective From the Field Document date: 2016_1_1
ID: riw5xs3j_3
Snippet: For hemorrhagic fevers, well-documented, relatively recent experience stems from a randomized controlled trial comparing CP (1 single unit of 500 mL) with normal plasma against Argentine hemorrhagic fever [7] . Mortality was 1.1% among the 91 patients who received CP compared to 16 .5% in the 97 patients treated with normal plasma. Of interest, a delayed neurological condition was observed in some patients after CP therapy, occurring several week.....
Document: For hemorrhagic fevers, well-documented, relatively recent experience stems from a randomized controlled trial comparing CP (1 single unit of 500 mL) with normal plasma against Argentine hemorrhagic fever [7] . Mortality was 1.1% among the 91 patients who received CP compared to 16 .5% in the 97 patients treated with normal plasma. Of interest, a delayed neurological condition was observed in some patients after CP therapy, occurring several weeks after apparent cure. CP has also been explored against the hemorrhagic disease Lassa fever, with conflicting results [8] [9] [10] [11] .
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