Author: Wu, Huajie; Li, Yan; Wang, Yanxia; Xu, Dunquan; Li, Congcong; Liu, Manling; Sun, Xin; Li, Zhichao
Title: Tanshinone IIA Attenuates Bleomycin-Induced Pulmonary Fibrosis via Modulating Angiotensin-Converting Enzyme 2/ Angiotensin-(1-7) Axis in Rats Document date: 2014_4_7
ID: td2uk2wc_33
Snippet: The protein levels of TGF-β1 were further verified by WB assays. The data showed that the protein levels of TGF-β1 were dramatically elevated after BLM administration (Fig. 6B) . However, TIIA treatment greatly inhibited TGF-β1 expression (Fig. 6B) . Similarly, BLM administration evidently increased the mRNA level of TGF-β1 in rat lungs (P<0.01, vs control group, Fig. 6C ), and TIIA treatment significantly reduced its expression (P<0.05, vs B.....
Document: The protein levels of TGF-β1 were further verified by WB assays. The data showed that the protein levels of TGF-β1 were dramatically elevated after BLM administration (Fig. 6B) . However, TIIA treatment greatly inhibited TGF-β1 expression (Fig. 6B) . Similarly, BLM administration evidently increased the mRNA level of TGF-β1 in rat lungs (P<0.01, vs control group, Fig. 6C ), and TIIA treatment significantly reduced its expression (P<0.05, vs BLM group, Fig. 6C ).
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