Author: Raison, C L; Miller, A H
Title: The evolutionary significance of depression in Pathogen Host Defense (PATHOS-D) Document date: 2012_1_31
ID: twgs7akl_27
Snippet: In a large study of consecutive patients admitted to hospital with fever, elevations in plasma concentrations of the anti-inflammatory cytokine IL-10-as well as the ratio of IL-10/TNF-a-were associated with increased mortality; 3 Increased IL-10 production late in the disease course predicted reduced survival following infection with the pandemic A/H1N1/2009 influenza virus. 4 Plasma concentration of C-reactive protein (CRP) via high-sensitivity .....
Document: In a large study of consecutive patients admitted to hospital with fever, elevations in plasma concentrations of the anti-inflammatory cytokine IL-10-as well as the ratio of IL-10/TNF-a-were associated with increased mortality; 3 Increased IL-10 production late in the disease course predicted reduced survival following infection with the pandemic A/H1N1/2009 influenza virus. 4 Plasma concentration of C-reactive protein (CRP) via high-sensitivity assay CRP is an acute-phase reactant primarily stimulated by IL-6 shown in multiple studies to predict the development of multiple illness associated with chronic inflammation CRP has been associated with increased survival in children with meningococcal sepsis. 276 Stimulated production of pro-and anti-inflammatory cytokines
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