Selected article for: "Envelope protein and structure protein"
Author: Teoh, Kim-Tat; Siu, Yu-Lam; Chan, Wing-Lim; Schlüter, Marc A.; Liu, Chia-Jen; Peiris, J. S. Malik; Bruzzone, Roberto; Margolis, Benjamin; Nal, Béatrice
Title: The SARS Coronavirus E Protein Interacts with PALS1 and Alters Tight Junction Formation and Epithelial Morphogenesis
  • Document date: 2010_11_15
    • ID: ufw13pjx_89
    Snippet: Our data describe a novel interaction between the small envelope E protein of the SARS coronavirus and the PALS1 tight junction protein strongly impacting the structure of mammalian epithelial cells. These insights contribute to a better understanding of the molecular mechanisms responsible for the abrupt deterioration of the lung epithelium in individuals infected by this deadly virus......
    Document: Our data describe a novel interaction between the small envelope E protein of the SARS coronavirus and the PALS1 tight junction protein strongly impacting the structure of mammalian epithelial cells. These insights contribute to a better understanding of the molecular mechanisms responsible for the abrupt deterioration of the lung epithelium in individuals infected by this deadly virus.

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